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Påmeldingsdato: 4. nov. 2022

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Leonotis leonurus, in your area typically referred to as "wilde dagga", is commonly made use of as a product, both topically and also orally, in the therapy of a wide range of conditions such as haemorrhoids, eczema, skin rashes, boils, itching, muscle aches, frustration, epilepsy, breast infections, crawler, constipation and snake bites. The dried flowers and also leaves are additionally smoked to soothe epilepsy. The flowers and leaves are reported to produce a moderate blissful result when smoked as well as have been claimed to have a similar, although less potent, psychoactive impact to marijuana. The phytochemistry of specifically the non-volatile constituents of leonotis leonurus has been thoroughly checked out because of passion created as a result of the wide range of biological effects reported for this plant. More than 50 compounds have actually been isolated and also characterised. L. leonurus consists of mostly terpenoids, specifically labdane diterpenes, the major diterpene reported is marrubiin. Various various other compounds have been reported by some authors to have been isolated from the plant, consisting of, in the prominent literature just, the gently psychoactive alkaloid, leonurine. Leonurine has nonetheless, never ever been reported by any clinical analysis of the removes of L. leonurus. The standard use by smoking likewise calls for further investigation as to exactly how the chemistry and also activity are affected by this kind of management. Research has actually proven the psychoactive impacts of the crude extract of L. leonurus, however confirmation of the visibility of psychoactive substances, as well as isolation as well as characterization, is still required. Much work is as a result still called for on the aspect of quality control to make certain safety, quality and also efficacy of the item provided to clients, as this plant is extensively used in South Africa as a conventional medicine. Readily offered plant sources give a feasible alternative for phytochemical study, particularly with regard to the suitable validation of the plant product in order to identify as well as delimit closely related varieties such as L. leonurus and also L. nepetifolia which are very similar in habit.

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